CDC42 Inhibitor III, ZCL278

CDC42 inhibitor

Cat. No.: AUR10255

CAS Number: 587841-73-4

Documents:

SizePrice

50 mg

$ 375

Tags ZCL278 CDC42 inhibitor CDC42 inhibitor CAS#587841-73-4 587841-73-4 Auroramedbiochem

Alternate Names

2-(4-bromo-2-chlorophenoxy)-N-[[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]carbamothioyl]acetamide; ZCL278

Appearance

Light beige solid

Formulation

N/A

CAS Number

587841-73-4

Molecular Formula

C21H19BrClN5O4S2

Molecular Weight

584.89

Purity

≥94% by HPLC

Solubility

DMSO (50 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

1791111

SMILES

CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C

InChI

InChI=1S/C21H19BrClN5O4S2/c1-12-9-13(2)25-20(24-12)28-34(30,31)16-6-4-15(5-7-16)26-21(33)27-19(29)11-32-18-8-3-14(22)10-17(18)23/h3-10H,11H2,1-2H3,(H,24,25,28)(H2,26,27,29,33)

InChI key

XKZDWYDHEBCGCG-UHFFFAOYSA-N

A potent, non-cytotoxic, pyrimidinylthiourea that targets Cdc42 GEF ITSN/intersectin and adjacent GTP/GDP binding site and effectively inhibits EGF-stimulated Cdc42 activity (1 h pretreatment; 50 µM) and Cdc42-dependent microspike/filopodia formation in serum-starved Swiss 3T3 fibroblast cultures without affecting RhoA- or Rac1-dependent functions.

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