Akt Inhibitor XIV

An Akt inhibitor

Cat. No.: AUR10072

CAS Number: 1191951-57-1

Documents:

SizePrice

50 mg

$ 395

Tags Akt Inhibitor XIV AKT INHIBITOR Akt inhibitor CAS#1191951-57-1 1191951-57-1 Auroramedbiocvhem

Alternate Names

4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

Appearance

White solid

Formulation

n/a

CAS Number

1191951-57-1

Molecular Formula

C20H31N3O2S2

Molecular Weight

409.61

Purity

≥95% by HPLC

Solubility

DMSO (50 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2°C to +8°C

Shipping Condition

Shelf life

24 months

MDL number

n/a

PubChem CID

44240850

SMILES

CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2

InChI

InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)

InChI key

BYWWNRBKPCPJMG-UHFFFAOYSA-N

A potent thiadiazolyl analog that binds to PH (pleckstrin homology) domain (Kd = 40.8 µM, Ki = 2.4 µM) and acts as a competitive and reversible blocker of Akt translocation to the cellular membrane with selectivity over PDK1 (Kd = 90.1 µM, Ki = 5.5 µM).